Mme ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMme ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Mme(Gene name) > Rat

Mme (Gene name),

Neprilysin (Protein name ), NEP_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mme;

Protein name:

Neprilysin;

Alternative:

Enkephalinase;Atriopeptidase;Skin fibroblast elastase(SFE);Neutral endopeptidase 24.11(NEP;Neutral endopeptidase);

CD:

CD10;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (By similarity). Involved in the degradation of atrial natriuretic factor (ANF).

Subcellular Location:

Cell membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

750

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P07861

UniGene:

Rn.33598

STRING:

10116.ENSRNOP00000044578

KEGG:

rno:24590

String:

P07861

Pfam:

PF01431

Uniprot:

P07861

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ELISA Kit for Rat Neprilysin

Cat.:

E1785h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat Neprilysin

Cat.:

E1785r

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Manual:

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Packing:

96T

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ELISA Kit for Rat Neprilysin

MSDS:

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ELISA Kit for Rat Neprilysin

MSDS:

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ELISA Kit for Rat Neprilysin

Cat.:

E1785m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Neprilysin

Cat.:

U1785m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Neprilysin

MSDS:

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CLIA Kit for Rat Neprilysin

Cat.:

U1785r

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat Neprilysin

MSDS:

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CLIA Kit for Rat Neprilysin

Cat.:

U1785h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Rat Neprilysin

Cat.:

P1785Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Neprilysin

Cat.:

P1785Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Neprilysin

Cat.:

P1785Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Neprilysin

Monoclonal Antibody for Rat Neprilysin

Protein for Rat Neprilysin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and amino acid sequence of rat enkephalinase."
Malfroy B. , Schofield P.R. , Kuang W.-J. , Seeburg P.H. , Mason A.J. , Henzel W.J.
Biochem. Biophys. Res. Commun.144:59-66(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Kidney.
3.

"Identification of the active-site arginine in rat neutral endopeptidase 24.11 (enkephalinase) as arginine 102 and analysis of a glutamine 102 mutant."
Bateman R.C. Jr. , Jackson D. , Slaughter C.A. , Unnithan S. , Chai Y.G. , Moomaw C. , Hersh L.B.
J. Biol. Chem.264:6151-6157(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITE ARG-103
4.

"Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity."
Rougeot C. , Messaoudi M. , Hermitte V. , Rigault A.G. , Blisnick T. , Dugave C. , Desor D. , Rougeon F.
Proc. Natl. Acad. Sci. U.S.A.100:8549-8554(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INHIBITION BY SIALORPHIN

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